|
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
|
| Volume 75 - Issue 14 |
| Published: August 2013 |
| Authors: L. Rufus Auxilia, T. Mowna Sundari, Rachel Regi Daniel |
10.5120/13180-0802
|
L. Rufus Auxilia, T. Mowna Sundari, Rachel Regi Daniel . Molecular Docking Studies of Dolichin A and B, Pterocarpans from Horsegram (Macrotyloma uniflorum) against HIV Replication Enzymes. International Journal of Computer Applications. 75, 14 (August 2013), 19-23. DOI=10.5120/13180-0802
@article{ 10.5120/13180-0802,
author = { L. Rufus Auxilia,T. Mowna Sundari,Rachel Regi Daniel },
title = { Molecular Docking Studies of Dolichin A and B, Pterocarpans from Horsegram (Macrotyloma uniflorum) against HIV Replication Enzymes },
journal = { International Journal of Computer Applications },
year = { 2013 },
volume = { 75 },
number = { 14 },
pages = { 19-23 },
doi = { 10.5120/13180-0802 },
publisher = { Foundation of Computer Science (FCS), NY, USA }
}
%0 Journal Article
%D 2013
%A L. Rufus Auxilia
%A T. Mowna Sundari
%A Rachel Regi Daniel
%T Molecular Docking Studies of Dolichin A and B, Pterocarpans from Horsegram (Macrotyloma uniflorum) against HIV Replication Enzymes%T
%J International Journal of Computer Applications
%V 75
%N 14
%P 19-23
%R 10.5120/13180-0802
%I Foundation of Computer Science (FCS), NY, USA
Isomeric pterocarpans, Dolichin A and Dolichin B of Macrotyloma uniflorum were docked with the three replication enzymes of HIV (Reverse transcriptase, Protease, Integrase). Analysed results proved that the docking score was high for Protease with Dolichin A (-6. 6899) and Dolichin B (-6. 6944) among Reverse transcriptase and Integrase. AIDS therapies could be scrutinized and /or replaced after the successful inihibitory effect of Dolichin. This study will support the cutting edge of HIV research and drug designing to find out a less side effect causing herbal formulations.